SubtiBank SubtiBank
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2017-09-16 18:39:052017-09-16 18:35:08

description

protein deacetylase and lipoamidase

protein deacetylase for the control of AcsA activity

function

control of [[protein|AcsA ]]activity

control of AcsA activity

product

NAD(+)-dependent deacetylase and lipoamidase

NAD( )-dependent AcsA deacetylase

Gene

Phenotypes of a mutant

increased 2-oxoglutarate dehydrogenase activity [pubmed|28900027]

The protein

Catalyzed reaction/ biological activity

NAD an acetylprotein = nicotinamide O-acetyl-ADP-ribose a protein (according to Swiss-Prot)

deacetylates (and thereby activates) [[protein|AcsA]] (together with [[protein|AcuC]]) [Pubmed|19136592]

removes lipoic acid from E2 subunits of ketoacid dehydrogenases and from the H protein of the glycine cleavage system

NAD an acetylprotein = nicotinamide O-acetyl-ADP-ribose a protein (according to Swiss-Prot) deacetylates (and thereby activates) [[protein|AcsA]] (together with [[protein|AcuC]]) [Pubmed|19136592]

References

19136592, 26708127, 12408821, 26098117, 28900027

19136592, 26708127, 12408821, 26098117

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